ID: ENSBTAT00000126387
Gene: ENSBTAG00000021343 Rho guanine nucleotide exchange factor 12 [Source:VGNC Symbol;Acc:VGNC:26106]
Polypeptide: ENSBTAT00000126387
15:30998137..31090062 1
| Ontology | ID | Term |
|---|---|---|
| molecular_function | GO:0001664 | G protein-coupled receptor binding |
| molecular_function | GO:0005085 | guanyl-nucleotide exchange factor activity |
| molecular_function | GO:0005096 | GTPase activator activity |
| molecular_function | GO:0005515 | protein binding |
| cellular_component | GO:0005737 | cytoplasm |
| biological_process | GO:0007186 | G protein-coupled receptor signaling pathway |
| biological_process | GO:0007266 | Rho protein signal transduction |
| biological_process | GO:0035556 | intracellular signal transduction |
| Protein database | Protein domain |
|---|---|
| COILS | Coil Coil |
| FUNFAM | G3DSA:2.30.29.30:FF:000072 null |
| FUNFAM | G3DSA:1.10.167.10:FF:000008 null |
| FUNFAM | G3DSA:2.30.42.10:FF:000033 null |
| FUNFAM | G3DSA:1.20.900.10:FF:000006 null |
| SMART | SM00233 PH_update |
| SMART | SM00228 pdz_new |
| SMART | SM00325 RhoGEF_3 |
| GENE3D | G3DSA:2.30.42.10 |
| PFAM | PF09128 RGS-like |
| PFAM | PF00595 PDZ |
| GENE3D | G3DSA:1.20.900.10 Dbl homology (DH) domain |
| PFAM | PF00621 RhoGEF |
| GENE3D | G3DSA:1.10.167.10 |
| GENE3D | G3DSA:2.30.29.30 |
| PFAM | PF17838 PH_16 |
| MOBIDB_LITE | mobidb-lite disorder_prediction |
| PANTHER | PTHR45872 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D |
| PROSITE_PATTERNS | PS00741 DH_1 |
| PROSITE_PROFILES | PS50010 DH_2 |
| PROSITE_PROFILES | PS50106 PDZ |
| PROSITE_PROFILES | PS50003 PH_DOMAIN |
| CDD | cd00160 RhoGEF |
| CDD | cd13390 PH_LARG |
| CDD | cd00992 PDZ_signaling |
| CDD | cd08754 RGS_LARG |
| SUPERFAMILY | SSF50729 PH domain-like |
| SUPERFAMILY | SSF50156 PDZ domain-like |
| SUPERFAMILY | SSF48097 Regulator of G-protein signaling, RGS |
| SUPERFAMILY | SSF48065 DBL homology domain (DH-domain) |